Community Health Interventions and Sickle Cell Agency, Inc., was founded in 1971 as Operation Sickle Cell, Inc., (CHISCA) as a voluntary, non-profit community-based organization with the goal of addressing needed services for individuals with hemoglobin diseases and other health disparities. The agency was chartered in 1975 to provide education, voluntary testing, and counseling. The founding Board members volunteered to educate, test, and provide genetic counseling and advocacy to the public and those affected. Since its inception, CHISCA, Inc. has relied heavily on the dedicated volunteers, committed professionals, and the community to further its services and activities. 
The Board of Directors represents some of the founders and other volunteers to include physicians, nurses, educators, ministers, counselors, and various other interested individuals.  CHISCA, Inc. has performed under a State Contract since 1975, committed to serving infants, children and their families diagnosed with Sickle Cell Disease and other hemoglobinia-pathies in Cumberland, Harnett, Hoke, and Robeson Counties

In 1988, CHISCA, Inc. expanded its mission to include HIV/STD prevention when it applied for and received its first grant from the North Carolina AIDS Control. This was the birth of the Cumberland County Minority AIDS Education Project, which is still in existence. 
Since its inception, the Project has consistently demonstrated success in setting obtainable application goals and objectives. The Project has also enjoyed great community support through a well-established credibility in the community with CHISCA, Inc. Past project, initiatives have focused on educating the public; women of childbearing age, adolescents, and street outreach targeting homosexuals, bisexuals, and illegal drug users and “crack” smokers. Success in reaching women who are partners of illegal drug users and “down-low” males (clandestine homosexuals) resulted in direct funding from the Centers for Disease Control & Prevention (CDC) (1999 – 2004).

CHISCA proposes to use additional grant funds to expand its goal of preventing the spread of HIV/AIDS and other STDs in Cumberland County, North Carolina, disproportionately affecting African Americans.